IL-18R Polyclonal Antibody

Interleukin-18 receptor 1 encoded by IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

The IL-18R Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IL-18R protein in various biological samples. This antibody is produced through a rigorous process of immunization with a synthetic peptide corresponding to a specific region of the IL-18R protein. It has been extensively validated for its specificity and affinity, ensuring reliable and reproducible results.

The IL-18R Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes the IL-18R protein with high affinity, enabling accurate and precise detection even at low expression levels. This antibody demonstrates minimal cross-reactivity with other related proteins, ensuring specificity in target recognition.

With its superior sensitivity and specificity, the IL-18R Polyclonal Antibody is an indispensable tool for researchers and scientists studying the IL-18R signaling pathway and its involvement in various physiological and pathological processes. Its reliable performance and consistent results make it an ideal choice for both basic research and clinical applications.

The IL-18R Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. This antibody is available in various sizes to accommodate different experimental needs.

In summary, the IL-18R Polyclonal Antibody is a highly specific and sensitive tool that enables accurate and reliable detection of IL-18R protein. Its exceptional performance and versatility make it an invaluable asset for researchers in the field of immunology and related disciplines.