IL-17R Alpha Polyclonal Antibody

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.

The IL-17R Alpha Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IL-17R Alpha protein in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.

IL-17R Alpha is a crucial receptor involved in the signaling pathway of interleukin-17 (IL-17), a pro-inflammatory cytokine. It plays a significant role in the regulation of immune responses and the development of various autoimmune and inflammatory diseases. The IL-17R Alpha Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various experimental settings, including Western blotting, immunohistochemistry, and flow cytometry.

With its exceptional performance, this antibody enables researchers to accurately analyze the expression and localization of IL-17R Alpha in different tissues and cell types. Its high affinity and low background ensure reliable and reproducible results, making it an ideal choice for both basic research and clinical applications.

The IL-17R Alpha Polyclonal Antibody is supplied as a liquid formulation, ready to use for various experimental techniques. It is provided in a convenient size and format, allowing for easy handling and storage. Each batch is meticulously quality-controlled to ensure consistent performance and reliability.

In summary, the IL-17R Alpha Polyclonal Antibody is a valuable tool for researchers studying the role of IL-17R Alpha in immune responses and inflammatory diseases. Its exceptional specificity, sensitivity, and reliability make it an indispensable asset in the field of immunology and biomedical research.