IL-16 Polyclonal Antibody

The protein encoded by IL16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.

The IL-16 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of interleukin-16 (IL-16) in various biological samples. IL-16 is a cytokine that plays a crucial role in immune response regulation and has been implicated in various diseases, including asthma, rheumatoid arthritis, and HIV infection.

This polyclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to a specific region of the IL-16 protein. It has been extensively validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA).

The IL-16 Polyclonal Antibody exhibits high affinity and selectivity towards IL-16, ensuring accurate and reliable results. It is suitable for both qualitative and quantitative analysis of IL-16 levels in biological samples, such as serum, plasma, tissue lysates, and cell culture supernatants.

With its superior performance characteristics, this antibody is an indispensable tool for researchers and clinicians studying the role of IL-16 in various physiological and pathological processes. Its application extends to basic research, drug development, and clinical diagnostics, providing valuable insights into the mechanisms underlying immune system dysregulation and potential therapeutic interventions.

The IL-16 Polyclonal Antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is recommended to store the antibody at -20°C for long-term stability. Each batch is quality controlled to ensure consistent performance, and detailed instructions for use are provided with each product.

In summary, the IL-16 Polyclonal Antibody is a reliable and efficient tool for the detection and quantification of IL-16 in various biological samples. Its high specificity, sensitivity, and versatility make it an essential component in research and clinical settings, facilitating advancements in the understanding and treatment of IL-16-associated diseases.