IL-13R Alpha2 Polyclonal Antibody

The interleukin 13 receptor subunit alpha 2 encoded by IL13RA2 is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.

The IL-13R Alpha2 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of IL-13R Alpha2 protein in various biological samples. This antibody has been extensively validated for its exceptional performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications.

IL-13R Alpha2, also known as Interleukin-13 receptor subunit alpha-2, is a transmembrane protein that plays a crucial role in the regulation of immune responses and inflammation. It is primarily expressed on the surface of immune cells, including macrophages, monocytes, and dendritic cells. IL-13R Alpha2 acts as a decoy receptor for IL-13, a cytokine involved in allergic and inflammatory diseases.

The IL-13R Alpha2 Polyclonal Antibody has been meticulously developed using high-quality immunogens and advanced purification techniques to ensure superior specificity and sensitivity. It exhibits minimal cross-reactivity with other related proteins, thereby enabling accurate and precise detection of IL-13R Alpha2 in complex biological samples.

This antibody demonstrates exceptional performance in IHC, allowing for the visualization and localization of IL-13R Alpha2 protein in tissue sections. It produces clear and distinct staining patterns, facilitating the identification of IL-13R Alpha2 expression in various cell types and tissues. Additionally, the antibody is compatible with multiple detection systems, providing flexibility and versatility in experimental design.

Furthermore, the IL-13R Alpha2 Polyclonal Antibody is highly suitable for IF applications, enabling the visualization of IL-13R Alpha2 protein in cultured cells and tissue sections. It offers excellent signal-to-noise ratio and minimal background, ensuring accurate and reliable results. The antibody can be used in combination with various fluorophores, allowing for multiplex staining and co-localization studies.

In WB applications, the IL-13R Alpha2 Polyclonal Antibody exhibits strong and specific band detection, enabling the quantification of IL-13R Alpha2 protein levels in cell lysates and tissue extracts. It demonstrates high sensitivity, detecting even low-abundance targets, and exhibits consistent performance across a wide range of sample concentrations.

In summary, the IL-13R Alpha2 Polyclonal Antibody is a valuable tool for researchers studying the role of IL-13R Alpha2 in immune responses and inflammation. Its exceptional specificity, sensitivity, and versatility make it an indispensable asset in various experimental techniques, including IHC, IF,