IL-12A Polyclonal Antibody

IL12A encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.

The IL-12A Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of interleukin-12A (IL-12A) protein in various biological samples. This antibody is produced through a rigorous process of immunization and purification, ensuring its high affinity and specificity towards IL-12A.

IL-12A is a crucial cytokine involved in the regulation of immune responses, particularly in the activation and differentiation of T cells and natural killer cells. Its dysregulation has been implicated in various diseases, including autoimmune disorders and certain types of cancer. Therefore, the accurate measurement of IL-12A levels is of utmost importance in both research and clinical settings.

The IL-12A Polyclonal Antibody exhibits exceptional performance in various immunoassays, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assays (ELISA). Its high sensitivity allows for the detection of low levels of IL-12A, enabling researchers to obtain reliable and reproducible results.

This antibody is supplied as a liquid formulation, ensuring ease of use and compatibility with different experimental protocols. It has been extensively validated in multiple applications and has shown excellent performance in various sample types, including cell lysates, tissue homogenates, and serum.

Furthermore, the IL-12A Polyclonal Antibody is manufactured under strict quality control standards, guaranteeing its consistency and reliability. It is produced using state-of-the-art techniques and undergoes rigorous testing to ensure batch-to-batch consistency, minimizing experimental variability.

In summary, the IL-12A Polyclonal Antibody is a highly specific and sensitive tool for the accurate detection and quantification of IL-12A protein. Its exceptional performance, ease of use, and stringent quality control make it an ideal choice for researchers and clinicians working in the field of immunology and related disciplines.