IL-10 Polyclonal Antibody

Interleukin-10 encoded by IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

The IL-10 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Interleukin-10 (IL-10) in various biological samples. IL-10 is a crucial cytokine involved in the regulation of immune responses and inflammation. This antibody is produced by immunizing animals with a synthetic peptide corresponding to a specific region of IL-10 protein.

The IL-10 Polyclonal Antibody exhibits exceptional affinity and selectivity towards IL-10, ensuring accurate and reliable results in various applications such as ELISA, Western blotting, immunohistochemistry, and flow cytometry. It has been extensively validated and optimized to provide consistent and reproducible performance.

This antibody offers numerous advantages, including high sensitivity, low background noise, and minimal cross-reactivity with other related proteins. It enables researchers to study the expression and function of IL-10 in different biological systems, aiding in the understanding of its role in various diseases and therapeutic interventions.

The IL-10 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and ease of handling. The antibody is manufactured under strict quality control standards, guaranteeing batch-to-batch consistency and reliability.

In summary, the IL-10 Polyclonal Antibody is an indispensable tool for researchers and scientists working in the field of immunology and inflammation. Its exceptional specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications, facilitating groundbreaking discoveries and advancements in the field.