IGF-I Polyclonal Antibody

The protein encoded by IGF1 is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

The IGF-I Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for the detection of insulin-like growth factor I (IGF-I) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human IGF-I. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in a variety of applications, including Western blotting, ELISA, and immunohistochemistry.

The IGF-I Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting IGF-I in various biological samples, including serum, plasma, and tissue extracts. This antibody has been shown to recognize both human and animal IGF-I, making it a versatile tool for researchers working in a variety of fields.

This antibody is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C for long-term storage and to avoid repeated freeze-thaw cycles.

Overall, the IGF-I Polyclonal Antibody is a reliable and high-quality tool for the detection of IGF-I in various biological samples. Its specificity and sensitivity make it an ideal choice for researchers working in the fields of endocrinology, cancer biology, and developmental biology.