IFITM3 Polyclonal Antibody

Interferon-induced transmembrane protein 3 encoded by IFITM3 is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined.

The IFITM3 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of IFITM3 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human IFITM3 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity by various assays, including Western blotting, immunohistochemistry, and immunofluorescence.

The IFITM3 protein is a member of the interferon-induced transmembrane protein family that plays a critical role in the innate immune response against viral infections. It is known to inhibit the entry of various viruses, including influenza A virus, West Nile virus, and dengue virus, into host cells. Therefore, the IFITM3 Polyclonal Antibody can be used to study the expression and localization of IFITM3 protein in different cell types and tissues under various physiological and pathological conditions.

This antibody is supplied as a liquid solution in phosphate-buffered saline (PBS) containing 0.02% sodium azide as a preservative. It is suitable for use in various applications, including Western blotting, immunohistochemistry, immunofluorescence, and ELISA. The IFITM3 Polyclonal Antibody is a valuable tool for researchers studying the innate immune response and viral infections.