IARS2 Polyclonal Antibody

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of isoleucine-tRNA synthetase exist, a cytoplasmic form and a mitochondrial form. IARS2 encodes the mitochondrial isoleucine-tRNA synthetase which belongs to the class-I aminoacyl-tRNA synthetase family.

The IARS2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of IARS2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human IARS2 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity by various assays, including Western blotting, immunohistochemistry, and immunofluorescence.

The IARS2 Polyclonal Antibody is suitable for a wide range of applications, including research in mitochondrial biology, protein synthesis, and neurodegenerative diseases. It has been shown to detect endogenous IARS2 protein in human, mouse, and rat tissues, as well as in cell lines. This antibody has also been used successfully in various experimental conditions, such as knockdown and overexpression studies.

The IARS2 Polyclonal Antibody is provided as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in different sizes and formats to meet the needs of different research applications. This antibody is a valuable tool for researchers studying IARS2 protein and its role in various biological processes.