HSP70 Polyclonal Antibody

This intronless gene HSPA1A(heat shock protein family A(Hsp70) member 1A) encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. HSPA1A is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

The HSP70 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Heat Shock Protein 70 (HSP70) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the HSP70 protein.

HSP70 is a highly conserved protein that plays a crucial role in cellular stress response and protein folding. It is involved in the protection and repair of damaged proteins, as well as the regulation of cellular processes such as apoptosis and cell cycle progression. The HSP70 Polyclonal Antibody recognizes both the constitutive and inducible forms of HSP70, making it an ideal tool for studying the expression and function of this important protein.

This antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results.

The HSP70 Polyclonal Antibody is supplied as a liquid formulation in a convenient size of 100 μg. It is provided in a ready-to-use format, eliminating the need for any additional preparation steps. The antibody is stored at -20°C to maintain its stability and activity.

In summary, the HSP70 Polyclonal Antibody is a valuable tool for researchers studying the role of HSP70 in cellular stress response and protein folding. Its high specificity, sensitivity, and versatility make it an essential component of any laboratory involved in the investigation of this important protein.