HSP70 (Acetyl Lys246) Polyclonal Antibody

HSPA1A encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, heat shock protein family A (Hsp70) member 1A stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. HSPA1A is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

The HSP70 (Acetyl Lys246) Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of HSP70 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the acetylated lysine 246 of HSP70 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The HSP70 protein is a member of the heat shock protein family that plays a crucial role in cellular stress response and protein folding. The acetylation of lysine 246 of HSP70 protein has been shown to regulate its chaperone activity and stability. Therefore, the HSP70 (Acetyl Lys246) Polyclonal Antibody is an essential tool for studying the function and regulation of HSP70 protein in various biological processes.

This antibody has been validated for use in Western blotting, immunoprecipitation, and immunofluorescence assays. It has been shown to specifically recognize the acetylated form of HSP70 protein and does not cross-react with other HSP70 family members or non-acetylated HSP70 protein. The HSP70 (Acetyl Lys246) Polyclonal Antibody is suitable for use in both research and diagnostic applications.

In summary, the HSP70 (Acetyl Lys246) Polyclonal Antibody is a high-quality antibody that provides specific and sensitive detection of acetylated HSP70 protein. Its excellent performance in various applications makes it an essential tool for studying the function and regulation of HSP70 protein in various biological processes.