HMP19 Polyclonal Antibody

The chondroitin sulfate proteoglycan NG2 is a type I membrane protein expressed by subpopulations of glia including oligodendroglial precursor cells and a variety of tumor cells. Normal precursor cells and malignant tumor cells migrate and proliferate, but there is evidence that cells may not be able to engage in both activities at the same time. However, NG2 is involved in promoting both proliferation and motility. The extracellular domain of NG2 sequesters growth factors and binds to both growth factor receptors and extracellular matrix ligands such as fibronectin, collagens and laminin. The cytoplasmic domain is involved in activating Rac, Cdc42 and p130 Cas. PKCα phosphorylates NG2 at Thr2256, triggering the redistribution of NG2 from apical microprocesses to lamellipodia accompanied by enhanced cell motility. ERK phosphorylates NG2 at Thr2314, stimulating cell proliferation.

The HMP19 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of HMP19 protein in various biological samples. This antibody has been meticulously developed and rigorously validated to ensure optimal performance and reliability.

The HMP19 Polyclonal Antibody exhibits exceptional affinity and selectivity towards the HMP19 protein, enabling accurate and precise measurement of its expression levels. It is produced using advanced recombinant DNA technology and purified through a series of stringent purification steps, resulting in a highly pure and concentrated antibody preparation.

This antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively tested and validated in various experimental conditions to ensure consistent and reproducible results. The HMP19 Polyclonal Antibody demonstrates excellent sensitivity, allowing for the detection of even low abundance HMP19 protein.

Furthermore, this antibody exhibits minimal cross-reactivity with other proteins, ensuring specific and reliable detection of HMP19. It is supplied in a convenient and user-friendly format, with clear instructions for optimal usage and storage conditions.

In summary, the HMP19 Polyclonal Antibody is a highly reliable and efficient tool for the detection and quantification of HMP19 protein. Its exceptional specificity, sensitivity, and ease of use make it an invaluable asset for researchers and scientists working in the field of immunology and protein analysis.