Histone H4 Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

The Histone H4 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of histone H4 protein in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards histone H4.

Histone H4 is a crucial component of nucleosomes, playing a vital role in chromatin structure and gene regulation. This antibody recognizes both the unmodified and modified forms of histone H4, making it an ideal choice for studying epigenetic modifications and their impact on gene expression.

The Histone H4 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It demonstrates minimal cross-reactivity with other histone proteins, ensuring accurate and reliable results.

With its superior sensitivity and specificity, this antibody enables researchers to delve into the intricate mechanisms of chromatin remodeling and epigenetic regulation. Its robust performance and versatility make it an indispensable tool for studies in molecular biology, genetics, and cancer research.

The Histone H4 Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and consistent results. It is available in various sizes to accommodate different experimental needs. Each batch of antibody undergoes rigorous quality control procedures to guarantee optimal performance and reproducibility.

Choose the Histone H4 Polyclonal Antibody for your research needs and unlock the potential of histone H4 in unraveling the complexities of gene regulation and epigenetic modifications.