Histone H4 (Mono Methyl Arg3) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST4H4 is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from HIST4H4 lack polyA tails; instead, they contain a palindromic termination element.

The Histone H4 (Mono Methyl Arg3) Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of histone H4 protein modifications. This antibody is designed to specifically recognize and bind to the mono methylated arginine residue at position 3 of histone H4.

Histone H4 is a core histone protein that plays a crucial role in chromatin structure and gene regulation. Post-translational modifications of histone H4, such as methylation, have been shown to be involved in various biological processes, including transcriptional activation and repression, DNA repair, and cell cycle regulation.

The Histone H4 (Mono Methyl Arg3) Polyclonal Antibody has been rigorously tested and validated for its specificity and sensitivity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with other histone H4 modifications, ensuring accurate and reliable results.

This antibody is produced using high-quality materials and state-of-the-art techniques, ensuring consistent performance and reproducibility. It is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage.

Whether you are studying histone modifications in basic research or investigating their potential as therapeutic targets, the Histone H4 (Mono Methyl Arg3) Polyclonal Antibody is an essential tool for your studies. Its high specificity, sensitivity, and reliability make it an invaluable asset in the field of epigenetics and chromatin biology.