Histone H3 Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H3A is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from HIST1H3A lack polyA tails; instead, they contain a palindromic termination element. HIST1H3A is found in the large histone gene cluster on chromosome 6p22-p21.3.

The Histone H3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of histone H3 protein in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and consistency in every batch.

Histone H3 is a crucial component of chromatin, playing a vital role in the regulation of gene expression and chromatin structure. This antibody recognizes the conserved epitopes of histone H3, allowing for precise and reliable detection of this protein in a wide range of applications, including immunohistochemistry, western blotting, and chromatin immunoprecipitation.

The Histone H3 Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate quantification and localization of histone H3 in both normal and disease-related samples. Its high affinity and low background make it an ideal choice for researchers and scientists working in the fields of epigenetics, cancer research, and developmental biology.

With its superior performance and reliability, the Histone H3 Polyclonal Antibody is an indispensable tool for studying the intricate mechanisms of gene regulation and chromatin dynamics. Trust in its exceptional quality to enhance your research and contribute to the advancement of scientific knowledge.