Histone H3 (Tri Methyl Lys14) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H3A (histone cluster 1 H3 family member a) is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. HIST1H3A is found in the large histone gene cluster on chromosome 6p22-p21.3.

The Histone H3 (Tri Methyl Lys14) Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of histone H3 protein modifications. This antibody is designed to specifically recognize and bind to the tri methylated lysine 14 residue on the histone H3 protein, allowing for the precise identification and quantification of this specific modification.

The Histone H3 (Tri Methyl Lys14) Polyclonal Antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and chromatin immunoprecipitation. Its high affinity and specificity ensure reliable and accurate results, making it an essential tool for researchers studying epigenetic modifications and their role in gene expression and cellular processes.

This antibody is produced using a polyclonal antibody production method, ensuring a diverse population of antibodies that can recognize multiple epitopes on the target protein. This enhances the sensitivity and versatility of the antibody, allowing for robust detection and analysis of histone H3 modifications.

The Histone H3 (Tri Methyl Lys14) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy integration into various experimental protocols. The antibody has been rigorously tested for quality and performance, ensuring consistent and reproducible results.

In summary, the Histone H3 (Tri Methyl Lys14) Polyclonal Antibody is a reliable and effective tool for the detection and analysis of histone H3 protein modifications. Its high specificity, sensitivity, and versatility make it an invaluable asset for researchers in the field of epigenetics and chromatin biology.