Histone H3 (Di Methyl Lys4) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H3A is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from HIST1H3A lack polyA tails; instead, they contain a palindromic termination element. HIST1H3A is found in the large histone gene cluster on chromosome 6p22-p21.3.

The Histone H3 (Di Methyl Lys4) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of histone H3 protein modifications. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the di methyl lysine 4 modification on histone H3.

Histone H3 is a crucial component of chromatin structure and plays a vital role in gene regulation and DNA packaging. The di methyl lysine 4 modification on histone H3 is associated with active gene transcription and is therefore of great interest in various research fields, including epigenetics, cancer biology, and developmental biology.

The Histone H3 (Di Methyl Lys4) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and chromatin immunoprecipitation. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of the di methyl lysine 4 modification on histone H3.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing waste. The antibody is also available in different formats, including bulk quantities, to meet the diverse needs of researchers.

With its exceptional performance and reliability, the Histone H3 (Di Methyl Lys4) Polyclonal Antibody is an indispensable tool for studying histone modifications and their role in gene regulation. It offers researchers a valuable resource for advancing their understanding of epigenetic mechanisms and their implications in various biological processes.