Histone H3 (Acetyl Lys14) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H3A (histone cluster 1 H3 family member a) is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from HIST1H3A lack polyA tails; instead, they contain a palindromic termination element. HIST1H3A is found in the large histone gene cluster on chromosome 6p22-p21.3.

The Histone H3 (Acetyl Lys14) Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of acetylated Lysine 14 on Histone H3. This antibody has been rigorously tested and validated for use in various applications, including Western blotting, immunohistochemistry, and chromatin immunoprecipitation.

Histone H3 is a core component of nucleosomes, which are the basic units of chromatin structure. Acetylation of Lysine 14 on Histone H3 has been implicated in various biological processes, including gene expression regulation, DNA repair, and cell cycle progression. The Histone H3 (Acetyl Lys14) Polyclonal Antibody specifically recognizes and binds to acetylated Lysine 14 on Histone H3, allowing for the precise detection and quantification of this post-translational modification.

This antibody has been produced using high-quality materials and state-of-the-art techniques to ensure optimal performance and reliability. It exhibits excellent sensitivity and specificity, enabling accurate and reproducible results. The antibody is supplied as a liquid formulation, making it easy to handle and use in various experimental settings.

The Histone H3 (Acetyl Lys14) Polyclonal Antibody is an essential tool for researchers studying epigenetics, chromatin biology, and gene regulation. Its high specificity and sensitivity make it ideal for investigating the role of acetylated Lysine 14 on Histone H3 in various cellular processes and disease states. With this antibody, researchers can gain valuable insights into the complex mechanisms underlying gene expression and chromatin dynamics.

Order the Histone H3 (Acetyl Lys14) Polyclonal Antibody today and enhance your research capabilities in the field of epigenetics.