Histone H2B (Tri Methyl Lys5) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H2BA is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from HIST1H2BA contain a palindromic termination element.

The Histone H2B (Tri Methyl Lys5) Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of histone H2B protein modifications. This antibody is produced using a polyclonal approach, ensuring a diverse population of antibodies that can recognize and bind to the target protein with high affinity and specificity.

Histone H2B is a core component of the nucleosome, which is the basic unit of chromatin structure. It plays a crucial role in regulating gene expression and chromatin organization. The tri-methylation of lysine 5 on histone H2B has been implicated in various biological processes, including transcriptional activation and DNA repair.

This polyclonal antibody has been rigorously validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and chromatin immunoprecipitation. It exhibits minimal cross-reactivity with other histone modifications, ensuring accurate and reliable results.

With its high quality and performance, the Histone H2B (Tri Methyl Lys5) Polyclonal Antibody is an essential tool for researchers studying epigenetics, chromatin biology, and gene regulation. Its versatility and reliability make it suitable for a wide range of applications in both basic research and clinical studies.

Order your Histone H2B (Tri Methyl Lys5) Polyclonal Antibody today and unlock new insights into the intricate world of histone modifications and their impact on cellular processes.