Histone H2A (Acetyl Lys9) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST1H2AI is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from HIST1H2AI lack polyA tails but instead contain a palindromic termination element. HIST1H2AI is found in the small histone gene cluster on chromosome 6p22-p21.3.

The Histone H2A (Acetyl Lys9) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of histone H2A protein acetylated at lysine 9. This antibody is produced through a rigorous process of immunization and purification, ensuring high affinity and specificity towards the target antigen.

Histone H2A is a crucial component of nucleosomes, the basic units of chromatin structure. Acetylation of lysine 9 on histone H2A has been implicated in various biological processes, including gene expression regulation, DNA repair, and chromatin remodeling. The Histone H2A (Acetyl Lys9) Polyclonal Antibody enables researchers to investigate the role of this specific histone modification in various cellular processes.

This antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other histone modifications, ensuring accurate and reliable results. Additionally, this antibody has been optimized for use in multiple species, including human, mouse, and rat, making it a versatile tool for a wide range of research applications.

The Histone H2A (Acetyl Lys9) Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a vial with an appropriate amount for multiple experiments, ensuring cost-effectiveness and reducing waste.

In summary, the Histone H2A (Acetyl Lys9) Polyclonal Antibody is a highly specific and sensitive tool that enables researchers to investigate the role of histone H2A acetylation at lysine 9 in various biological processes. With its excellent performance and versatility, this antibody is an essential resource for researchers in the field of epigenetics and chromatin biology.