Histone H2A (Acetyl Lys5) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST1H2AI is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from HIST1H2AI lack polyA tails but instead contain a palindromic termination element. HIST1H2AI is found in the small histone gene cluster on chromosome 6p22-p21.3.

The Histone H2A (Acetyl Lys5) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Histone H2A protein acetylated at Lysine 5. This antibody is produced using high-quality polyclonal antibodies that have been carefully selected and validated for their specificity and sensitivity.

Histone H2A is a core component of the nucleosome, which is the basic unit of chromatin structure. Acetylation of Histone H2A at Lysine 5 has been implicated in various biological processes, including gene expression regulation, DNA repair, and chromatin remodeling. Therefore, the detection and analysis of Histone H2A acetylated at Lysine 5 are of great importance in understanding the underlying mechanisms of these processes.

The Histone H2A (Acetyl Lys5) Polyclonal Antibody has been extensively tested and validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits high specificity and sensitivity, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, making it easy to use and handle. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. Additionally, it is compatible with various sample types, including cell lysates, tissue extracts, and purified proteins.

In summary, the Histone H2A (Acetyl Lys5) Polyclonal Antibody is a valuable tool for researchers studying histone modifications and their role in various biological processes. Its high specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications.