Histone H2A (Acetyl Lys15) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST1H2AI is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from HIST1H2AI lack polyA tails but instead contain a palindromic termination element. HIST1H2AI is found in the small histone gene cluster on chromosome 6p22-p21.3.

The Histone H2A (Acetyl Lys15) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Histone H2A protein acetylated at Lysine 15. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target protein.

Histone H2A is a crucial component of nucleosomes, which are the basic units of chromatin structure. Acetylation of Lysine 15 on Histone H2A has been implicated in various biological processes, including gene regulation, DNA repair, and chromatin remodeling. Therefore, the detection and quantification of Histone H2A acetylated at Lysine 15 is of great importance in understanding these fundamental cellular processes.

The Histone H2A (Acetyl Lys15) Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence. It has been rigorously validated for its specificity and sensitivity, ensuring reliable and reproducible results.

With its high-quality formulation and optimized protocols, this antibody offers researchers a valuable tool for investigating the role of Histone H2A acetylation in various biological contexts. Its superior performance and reliability make it an indispensable asset for studies in epigenetics, chromatin biology, and gene regulation.

Order the Histone H2A (Acetyl Lys15) Polyclonal Antibody today and unlock new insights into the intricate mechanisms of cellular processes regulated by Histone H2A acetylation.