HC-II Polyclonal Antibody

SERPIND1 belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. SERPIND1 encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency.

The HC-II Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in various research applications. This antibody is produced by immunizing animals with a purified recombinant protein of the HC-II gene, resulting in a polyclonal antibody that recognizes the HC-II protein with high affinity and specificity.

The HC-II Polyclonal Antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and ELISA. It has been shown to detect endogenous levels of HC-II protein in various tissues and cell lines, making it an ideal tool for studying the expression and function of HC-II in various biological systems.

This antibody is supplied as a purified IgG fraction, which has been affinity-purified from serum using protein A chromatography. It is provided in a convenient format, with a concentration of 1 mg/mL, making it easy to use in a variety of applications.

Overall, the HC-II Polyclonal Antibody is a reliable and high-quality tool for researchers studying the HC-II protein and its role in various biological processes. Its high specificity and sensitivity make it an ideal choice for a wide range of applications, and its convenient format makes it easy to use in any laboratory setting.