GRF-1 Polyclonal Antibody

The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids.

The GRF-1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Growth Hormone Releasing Factor 1 (GRF-1) in various biological samples. This antibody is produced using state-of-the-art techniques, ensuring high affinity and specificity towards the target protein.

The GRF-1 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Its superior sensitivity allows for the accurate measurement of GRF-1 levels even in low abundance samples.

This antibody is meticulously validated to ensure consistent and reliable results. It has been extensively tested against a variety of species, including human, mouse, and rat, guaranteeing its broad applicability across different research fields.

The GRF-1 Polyclonal Antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming preparation. Its long shelf life and stability ensure consistent performance over an extended period, making it an ideal choice for long-term experiments.

With its exceptional specificity, sensitivity, and versatility, the GRF-1 Polyclonal Antibody is an indispensable tool for researchers and scientists studying the role of GRF-1 in various physiological and pathological processes.