BT Lab
SKU:BT-AP03804
GRB14 Polyclonal Antibody
GRB14 Polyclonal Antibody
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Growth factor receptor-bound protein 14 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. GRB14 encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Growth factor receptor-bound protein 14 likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. GRB14 may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.
The GRB14 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of GRB14 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target protein.
GRB14, also known as growth factor receptor-bound protein 14, is a key adaptor protein involved in multiple cellular signaling pathways. It plays a crucial role in regulating insulin signaling, cell growth, and metabolism. Dysregulation of GRB14 has been implicated in various diseases, including diabetes, obesity, and cancer.
The GRB14 Polyclonal Antibody is validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent performance in detecting endogenous levels of GRB14 in both human and animal tissues.
This antibody is manufactured under strict quality control standards to ensure consistent and reliable results. It is supplied as a liquid formulation, ready to use for immediate experimentation. Each vial contains sufficient antibody for multiple experiments, minimizing the need for frequent reordering.
With its exceptional sensitivity and specificity, the GRB14 Polyclonal Antibody is an indispensable tool for researchers studying the role of GRB14 in cellular signaling and its implications in disease pathogenesis.
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