Granuphilin Polyclonal Antibody

SYTL4 (synaptotagmin like 4) encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein.

The Granuphilin Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Granuphilin protein in various biological samples. This antibody is produced using state-of-the-art techniques, ensuring high affinity and specificity towards the target protein.

Granuphilin, also known as synaptotagmin-like protein 4 (SYTL4), plays a crucial role in the regulation of insulin exocytosis in pancreatic beta cells. It is involved in the docking and fusion of insulin-containing granules with the plasma membrane, thereby facilitating the release of insulin into the bloodstream.

The Granuphilin Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of Granuphilin protein in complex biological samples.

This antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and error-prone reconstitution steps. The antibody is also available in different sizes to accommodate various experimental needs.

With its exceptional performance and reliability, the Granuphilin Polyclonal Antibody is an indispensable tool for researchers studying the role of Granuphilin in insulin exocytosis and related processes. Its high specificity and sensitivity make it an ideal choice for both basic research and clinical applications.

Order the Granuphilin Polyclonal Antibody today and unlock new insights into the intricate mechanisms underlying insulin secretion and diabetes pathogenesis.