GPR133 Polyclonal Antibody

The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins (summary by Bjarnadottir et al. 2004 [PubMed 15203201]).

The GPR133 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of GPR133 protein expression in various biological samples. This antibody is produced using state-of-the-art techniques, ensuring high affinity and specificity towards GPR133.

GPR133, also known as ADGRD1, is a G protein-coupled receptor that plays a crucial role in various physiological processes, including cell proliferation, differentiation, and migration. It is predominantly expressed in the central nervous system, particularly in the brain, where it is involved in neuronal development and function. Dysregulation of GPR133 has been implicated in several neurological disorders, making it an important target for research and therapeutic interventions.

The GPR133 Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of GPR133 protein expression in both normal and diseased tissues.

This antibody is supplied as a liquid formulation, ready to use for immediate experimentation. It is provided in a convenient size, allowing for multiple experiments without compromising its quality. The GPR133 Polyclonal Antibody is compatible with a wide range of sample types, including cell lysates, tissue homogenates, and cultured cells.

In summary, the GPR133 Polyclonal Antibody is a valuable tool for researchers studying GPR133 protein expression and its role in various biological processes. Its high specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications.