Glut4 Polyclonal Antibody

SLC2A4 is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).

The Glut4 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Glut4 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Glut4 protein. The antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Glut4 Polyclonal Antibody is a valuable tool for researchers studying glucose metabolism and insulin signaling pathways. Glut4 is a glucose transporter protein that plays a critical role in glucose uptake and utilization in insulin-sensitive tissues such as skeletal muscle and adipose tissue. Dysregulation of Glut4 expression and function has been implicated in various metabolic disorders, including diabetes and obesity.

This antibody is supplied as a purified IgG fraction, which has been affinity-purified using immobilized protein A. The antibody is provided in a liquid format and can be stored at -20°C for long-term storage. The Glut4 Polyclonal Antibody is available in various sizes to meet the needs of different research applications.

In summary, the Glut4 Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for the detection of Glut4 protein in various biological samples. This antibody is a valuable tool for researchers studying glucose metabolism and insulin signaling pathways and can be used in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.