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SKU:BT-AP03604

Glut3 Polyclonal Antibody

Glut3 Polyclonal Antibody

Regular price $275.00 USD
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GLUT3 (SLC2A3) belongs to the glucose transporter family (GLUTs) which mediates the transport of glucose across cellular membranes in mammalian cells. There are three subclasses within GLUTs: class I comprises the classical transporters GLUT1-4 and GLUT14; class II contains the "odd" isoforms GLUT5, 7, 9, and 11; the isoforms GLUT6, 8, 10, 12 and the proton driven myoinositol transporter HMIT (GLUT13) belong to class III. GLUT3 is considered as a neuron-specific glucose transporter because of its dominant expression in the brain in various species. However, besides the brain GLUT3 is also expressed in tissues with high demand for glucose such as sperm, preimplantation embryos, circulating white blood cells, and an array of carcinoma cell lines. ecently GLUT3 has been identified as a sensitive and specific marker for embyonal carcinomas and yolk tumors. he GLUT14 is believed to be the duplicate gene of GLUT3 given to the high identity in sequence between them. This antibody was generated against the internal region of human GLUT3 and may cross-react with GLUT14.

The Glut3 Polyclonal Antibody is a highly specific and reliable tool for the detection and quantification of Glut3 protein expression in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, making it an ideal choice for researchers in the field of molecular biology and biochemistry.

The Glut3 Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been rigorously tested for cross-reactivity with other Glut isoforms, ensuring accurate and reliable results. This antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its superior performance characteristics, the Glut3 Polyclonal Antibody enables precise and reproducible quantification of Glut3 protein levels in a wide range of samples, including cell lysates, tissue homogenates, and biological fluids. Its high affinity and specificity for Glut3 make it an invaluable tool for studying glucose transport and metabolism in various physiological and pathological conditions.

The Glut3 Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided in a liquid form, ready-to-use, and does not require any additional reagents or preparation steps. Each vial contains a sufficient amount of antibody for multiple experiments, ensuring cost-effectiveness and minimizing waste.

In summary, the Glut3 Polyclonal Antibody is a reliable and highly specific tool for the detection and quantification of Glut3 protein expression. Its exceptional performance characteristics, ease of use, and versatility make it an essential reagent for researchers investigating glucose transport and metabolism.

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