GLI-3 Polyclonal Antibody

GLI3 encodes GLI family zinc finger 3 which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.

The GLI-3 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of GLI-3 protein expression in various biological samples. This antibody has been meticulously developed and validated to ensure optimal performance and accuracy in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The GLI-3 Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling the precise identification and quantification of GLI-3 protein levels in both normal and disease states. Its polyclonal nature allows for enhanced recognition of multiple epitopes, ensuring robust and consistent results across different experimental conditions.

This antibody has been rigorously tested and validated using a variety of experimental approaches, guaranteeing its reliability and reproducibility. It has demonstrated excellent performance in detecting endogenous GLI-3 protein in various cell lines and tissues, making it an invaluable tool for researchers studying the role of GLI-3 in developmental biology, cancer research, and other related fields.

The GLI-3 Polyclonal Antibody is produced using state-of-the-art techniques and undergoes stringent quality control measures to ensure batch-to-batch consistency and high purity. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation.

With its exceptional performance, reliability, and ease of use, the GLI-3 Polyclonal Antibody is an indispensable tool for researchers seeking to unravel the intricate mechanisms underlying GLI-3 protein function and its involvement in various biological processes.