GDF-7 Polyclonal Antibody

GDF7 encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signaling molecules that regulate diverse processes in growth, repair and embryonic development. The encoded preproprotein is proteolytically processed to generate the mature protein, which may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma.

The GDF-7 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Growth Differentiation Factor 7 (GDF-7) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human GDF-7 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in various applications, including Western blotting, immunohistochemistry, and ELISA.

The GDF-7 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting GDF-7 protein in various tissues and cell lines. It has been shown to recognize both the mature and precursor forms of GDF-7 protein, making it a valuable tool for studying the regulation and function of this protein in various biological processes.

This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C or below for long-term storage and to avoid repeated freeze-thaw cycles.

In summary, the GDF-7 Polyclonal Antibody is a reliable and high-quality antibody that can be used for the detection of GDF-7 protein in various biological samples. Its specificity and sensitivity make it an ideal tool for researchers studying the role of GDF-7 in various biological processes.