GCS-Beta-2 Polyclonal Antibody

Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.

The GCS-Beta-2 Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a region of the GCS-Beta-2 protein. The resulting polyclonal antibody has been purified using a combination of protein A and peptide affinity chromatography to ensure high specificity and purity.

The GCS-Beta-2 Polyclonal Antibody has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays. It has been shown to specifically recognize the GCS-Beta-2 protein in a variety of tissues and cell types, making it an ideal tool for studying the expression and function of this protein.

This antibody is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to meet the needs of different research applications. The GCS-Beta-2 Polyclonal Antibody is a reliable and high-quality reagent that can help researchers advance their understanding of the GCS-Beta-2 protein and its role in various biological processes.