GCP4 Polyclonal Antibody

TUBGCP4 encodes a component of the gamma-tubulin ring complex, gamma-tubulin complex component 4, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.

The GCP4 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of GCP4 protein expression in various biological samples. This antibody has been meticulously developed and validated to ensure exceptional performance and accuracy in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The GCP4 Polyclonal Antibody exhibits a high affinity and specificity towards GCP4, a key protein involved in the regulation of microtubule dynamics and spindle assembly during cell division. By targeting GCP4, this antibody enables researchers to gain valuable insights into the intricate mechanisms underlying cell division and mitotic spindle formation.

This antibody has been rigorously tested and validated to ensure its superior performance and reliability. It exhibits minimal cross-reactivity with other proteins, ensuring precise and specific detection of GCP4 in complex biological samples. Furthermore, it demonstrates excellent sensitivity, allowing for the detection of low levels of GCP4 expression.

The GCP4 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, allowing for easy storage and handling. The antibody is compatible with a variety of experimental conditions and can be used with confidence in both routine laboratory settings and advanced research applications.

In summary, the GCP4 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of GCP4 protein expression. Its exceptional performance, sensitivity, and versatility make it an invaluable asset for researchers studying cell division, mitotic spindle assembly, and related biological processes.