GABAA R Delta Polyclonal Antibody

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. GABRD encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.

The GABAA R Delta Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of GABAA receptor delta subunit. This antibody is produced using advanced techniques to ensure superior quality and performance.

The GABAA receptor delta subunit plays a crucial role in the functioning of the GABAA receptor, a major inhibitory neurotransmitter receptor in the central nervous system. By targeting this specific subunit, the GABAA R Delta Polyclonal Antibody allows for the investigation of its expression, localization, and regulation in various biological samples.

This antibody has been extensively validated for its specificity and sensitivity in a range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other GABAA receptor subunits, ensuring accurate and reliable results.

The GABAA R Delta Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. The antibody is stored at optimal conditions to maintain its stability and functionality.

With its exceptional performance and reliability, the GABAA R Delta Polyclonal Antibody is an indispensable tool for researchers studying the GABAA receptor delta subunit and its involvement in various physiological and pathological processes.