GABAA R Gamma1 Polyclonal Antibody

The gamma-aminobutyric acid type A receptor gamma1 subunit encoded by GABRG1 belongs to the ligand-gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. GABRG1 is clustered with three other family members on chromosome 4.

The GABAA R Gamma1 Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect the Gamma1 subunit of the GABAA receptor. This antibody has been extensively tested and validated for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The GABAA receptor is a ligand-gated ion channel that plays a critical role in the regulation of neuronal excitability and synaptic transmission. The Gamma1 subunit is one of several subunits that make up the GABAA receptor, and it is known to be involved in the modulation of receptor function and trafficking.

This polyclonal antibody has been raised against a synthetic peptide corresponding to the C-terminal region of the Gamma1 subunit of the GABAA receptor. It has been purified using a combination of protein A and peptide affinity chromatography, ensuring high specificity and sensitivity.

The GABAA R Gamma1 Polyclonal Antibody is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in a range of sizes to suit your specific needs.

Overall, the GABAA R Gamma1 Polyclonal Antibody is a reliable and effective tool for the detection and analysis of the Gamma1 subunit of the GABAA receptor. Its high specificity and sensitivity make it an ideal choice for researchers studying the role of this subunit in neuronal function and disease.