GABAA R Alpha1 Polyclonal Antibody

GABRA1 encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.

The GABAA R Alpha1 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of GABAA receptor alpha1 subunit. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The GABAA R Alpha1 Polyclonal Antibody is ideal for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is designed to recognize the GABAA receptor alpha1 subunit, which is a key component of the GABAA receptor complex. The GABAA receptor is a ligand-gated ion channel that mediates the inhibitory effects of the neurotransmitter gamma-aminobutyric acid (GABA) in the central nervous system. The alpha1 subunit is one of the most abundant subunits of the GABAA receptor and is involved in the modulation of GABAergic neurotransmission.

The GABAA R Alpha1 Polyclonal Antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. This antibody has been shown to be highly specific for the GABAA receptor alpha1 subunit and does not cross-react with other GABAA receptor subunits or other proteins.

In summary, the GABAA R Alpha1 Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for the detection of GABAA receptor alpha1 subunit in a wide range of applications. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity, making it a reliable tool for researchers studying the GABAA receptor complex and its role in the central nervous system.