Frizzled-4 Polyclonal Antibody

FZD4 (frizzled class receptor 4) is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.

The Frizzled-4 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Frizzled-4 protein expression in various biological samples. This antibody is produced through a rigorous process of immunization and purification, ensuring its high affinity and specificity towards Frizzled-4 protein.

Frizzled-4 is a member of the Frizzled family of proteins, which are crucial components of the Wnt signaling pathway. This pathway plays a vital role in various cellular processes, including embryonic development, tissue homeostasis, and cell proliferation. Dysregulation of the Wnt signaling pathway has been implicated in numerous diseases, including cancer and developmental disorders.

The Frizzled-4 Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of Frizzled-4 protein expression in both normal and diseased tissues.

This antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. The Frizzled-4 Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in both research and clinical settings.

With its exceptional performance and reliability, the Frizzled-4 Polyclonal Antibody is an indispensable tool for researchers and clinicians studying the Wnt signaling pathway and its implications in various diseases. Its high specificity and sensitivity make it an ideal choice for investigating Frizzled-4 protein expression and its potential role in disease progression and therapeutic targeting.