Frizzled-2 Polyclonal Antibody

FZD2 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. FZD2 encodes frizzled class receptor 2 that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways. is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.

The Frizzled-2 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Frizzled-2 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards Frizzled-2.

Frizzled-2 is a crucial component of the Wnt signaling pathway, playing a pivotal role in embryonic development, tissue homeostasis, and cell proliferation. Dysregulation of Frizzled-2 expression has been implicated in various diseases, including cancer and neurological disorders. Therefore, the Frizzled-2 Polyclonal Antibody serves as an invaluable tool for researchers and clinicians investigating the role of Frizzled-2 in disease pathogenesis and therapeutic interventions.

The Frizzled-2 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It demonstrates high sensitivity and specificity, enabling accurate and reliable detection of Frizzled-2 protein expression in both normal and diseased tissues.

This antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. The Frizzled-2 Polyclonal Antibody is compatible with various detection systems and can be used in conjunction with other antibodies for multiplex analysis.

In summary, the Frizzled-2 Polyclonal Antibody is a superior research tool that enables precise and efficient investigation of Frizzled-2 protein expression. Its exceptional sensitivity, specificity, and versatility make it an indispensable asset for researchers and clinicians in the field of molecular biology, cancer research, and drug discovery.