Fibulin-4 Polyclonal Antibody

A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The EGF containing fibulin like extracellular matrix protein 2 encoded by EFEMP2 contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene.

The Fibulin-4 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Fibulin-4 protein in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.

Fibulin-4 is a crucial extracellular matrix protein that plays a significant role in maintaining tissue integrity and function. It is involved in various physiological processes, including cell adhesion, migration, and tissue development. Dysregulation of Fibulin-4 has been implicated in several pathological conditions, such as cardiovascular diseases and connective tissue disorders.

The Fibulin-4 Polyclonal Antibody exhibits exceptional specificity towards Fibulin-4, enabling accurate and reliable detection in immunohistochemistry (IHC), western blotting, and other relevant applications. It recognizes both native and denatured forms of Fibulin-4, making it suitable for a wide range of experimental settings.

This antibody is validated for use in multiple species, including human, mouse, and rat, ensuring its versatility and applicability in various research fields. It exhibits minimal cross-reactivity with other related proteins, ensuring precise and specific results.

The Fibulin-4 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without compromising its quality. Each batch is rigorously tested to meet the highest standards of quality control, ensuring consistent performance and reproducibility.

In summary, the Fibulin-4 Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of Fibulin-4 protein. Its high specificity, sensitivity, and versatility make it an invaluable asset for researchers in the fields of molecular biology, biochemistry, and biomedical sciences.