Fhit Polyclonal Antibody

FHIT, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.

The Fhit Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of the Fhit protein in various biological samples. This antibody is produced through a rigorous process of immunization and purification, ensuring its high affinity and specificity towards the Fhit protein.

The Fhit protein is a tumor suppressor that plays a crucial role in maintaining genomic stability and preventing the development of cancer. Its aberrant expression or loss has been implicated in various types of cancers, making it an important target for research and diagnostic purposes.

The Fhit Polyclonal Antibody offers exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its superior sensitivity allows for the detection of even low levels of Fhit protein, enabling accurate quantification and analysis.

This antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures to ensure its reliability and reproducibility. It exhibits minimal cross-reactivity with other proteins, ensuring specific and accurate results.

The Fhit Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into laboratory workflows. It is provided in a liquid formulation, eliminating the need for reconstitution and minimizing the risk of sample contamination.

With its exceptional specificity, sensitivity, and ease of use, the Fhit Polyclonal Antibody is an indispensable tool for researchers and clinicians involved in cancer research, biomarker discovery, and diagnostic applications. Trust in its performance to advance your understanding of Fhit protein biology and contribute to the development of novel therapeutic strategies.