FGFR-5 Polyclonal Antibody

The protein encoded by FGFRL1 (fibroblast growth factor receptor-like 1) is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between FGFRL1 product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for FGFRL1.

The FGFR-5 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of FGFR-5 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards FGFR-5.

The FGFR-5 Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and minimal cross-reactivity with other FGFR family members, making it an ideal choice for accurate and reliable detection of FGFR-5 protein.

This antibody is manufactured under strict quality control standards, ensuring consistent and reproducible results. It is supplied as a liquid formulation, ready to use for immediate application. The FGFR-5 Polyclonal Antibody is available in various sizes to meet the specific needs of researchers and scientists.

With its exceptional performance and reliability, the FGFR-5 Polyclonal Antibody is an indispensable tool for studying the role of FGFR-5 in various biological processes and diseases. Its high specificity and sensitivity make it an invaluable asset for researchers in the fields of cancer biology, developmental biology, and signal transduction pathways.

Choose the FGFR-5 Polyclonal Antibody for accurate and reliable detection of FGFR-5 protein expression, and unlock new insights into the intricate mechanisms underlying cellular processes.