Fatty Acid Synthase Polyclonal Antibody

Fatty acid synthase encoded by FASN is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

The Fatty Acid Synthase Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Fatty Acid Synthase (FASN) protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring its high affinity and sensitivity towards FASN.

Fatty Acid Synthase is a key enzyme involved in de novo fatty acid synthesis, playing a crucial role in lipid metabolism. Dysregulation of FASN has been implicated in various diseases, including cancer, obesity, and metabolic disorders. Therefore, the accurate measurement of FASN expression is of paramount importance in understanding the underlying mechanisms and developing targeted therapies.

The Fatty Acid Synthase Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes both the native and denatured forms of FASN, enabling comprehensive analysis of protein expression in different experimental settings.

This antibody demonstrates minimal cross-reactivity with other related proteins, ensuring specific and reliable results. It exhibits excellent sensitivity, allowing for the detection of even low levels of FASN expression. Additionally, it exhibits a long shelf life and stability, ensuring consistent and reproducible results over time.

The Fatty Acid Synthase Polyclonal Antibody is supplied in a convenient and ready-to-use format, facilitating ease of use and saving valuable time in the laboratory. It is compatible with various sample types, including cell lysates, tissue extracts, and purified proteins.

In summary, the Fatty Acid Synthase Polyclonal Antibody is a highly valuable tool for researchers and scientists involved in the study of lipid metabolism, cancer biology, and metabolic disorders. Its exceptional specificity, sensitivity, and versatility make it an indispensable asset in elucidating the role of FASN in various physiological and pathological processes.