FAM111B Polyclonal Antibody

FAM111B encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin-like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.

The FAM111B Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of FAM111B protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring high affinity and sensitivity. It has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The FAM111B Polyclonal Antibody exhibits exceptional performance in detecting endogenous levels of FAM111B protein in human, mouse, and rat tissues. It recognizes a conserved epitope within the FAM111B protein, enabling accurate and reproducible results across different species.

With its superior specificity, this antibody offers researchers a valuable tool for studying the role of FAM111B in various cellular processes and disease mechanisms. Its versatility allows for the investigation of FAM111B expression patterns in normal and pathological conditions, aiding in the understanding of its functional significance.

The FAM111B Polyclonal Antibody is supplied as a liquid formulation, ensuring ease of use and convenience. It is provided in a ready-to-use format, eliminating the need for time-consuming preparation steps. The antibody is also available in different sizes to accommodate various experimental requirements.

In summary, the FAM111B Polyclonal Antibody is a reliable and specific tool for the detection and analysis of FAM111B protein expression. Its high affinity, sensitivity, and versatility make it an ideal choice for researchers studying FAM111B in various biological contexts.