BT Lab
SKU:BT-AP03129
FADD Polyclonal Antibody
FADD Polyclonal Antibody
Couldn't load pickup availability
Protein FADD encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, protein FADD can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of protein FADD with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
The FADD Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Fas-associated death domain (FADD) protein. This antibody is produced using advanced techniques to ensure exceptional quality and performance.
The FADD Polyclonal Antibody exhibits a high affinity towards FADD protein, enabling accurate and sensitive detection in various experimental applications. It has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence assays.
With its superior specificity, the FADD Polyclonal Antibody offers researchers a valuable tool for studying the role of FADD in various cellular processes, including apoptosis and immune response. Its exceptional sensitivity allows for the detection of even low levels of FADD protein, facilitating precise quantification and analysis.
Furthermore, the FADD Polyclonal Antibody is manufactured under strict quality control measures to ensure batch-to-batch consistency and reproducibility. Each lot is rigorously tested to meet the highest standards of performance, providing researchers with reliable and consistent results.
In summary, the FADD Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of FADD protein. Its exceptional quality, sensitivity, and specificity make it an invaluable asset for researchers studying the intricate mechanisms of apoptosis and immune response.
Share
