EWS Polyclonal Antibody

EWSR1 encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically at (11;22) (q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.

The EWS Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of the EWS protein. This antibody is produced using a polyclonal approach, ensuring a diverse range of binding sites to enhance sensitivity and accuracy in various applications.

The EWS Polyclonal Antibody exhibits exceptional affinity towards the EWS protein, enabling precise identification and quantification of this target molecule. It has been extensively validated for use in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) techniques, guaranteeing consistent and reproducible results.

With its superior performance, the EWS Polyclonal Antibody offers researchers and clinicians an invaluable tool for investigating the role of the EWS protein in various biological processes and diseases. Its robustness and versatility make it suitable for a wide range of sample types, including tissue sections, cell cultures, and whole-cell lysates.

Furthermore, the EWS Polyclonal Antibody is manufactured under stringent quality control measures to ensure batch-to-batch consistency and reliability. Each lot is rigorously tested to meet the highest standards of specificity, sensitivity, and reproducibility, providing users with confidence in their experimental outcomes.

In summary, the EWS Polyclonal Antibody is a cutting-edge research tool that enables accurate and efficient detection of the EWS protein. Its exceptional performance, versatility, and stringent quality control make it an indispensable asset for scientists and clinicians alike in their pursuit of unraveling the complexities of EWS-related biology and pathology.