ETO-2 Polyclonal Antibody

CBFA2T3 (CBFA2/RUNX1 translocation partner 3) encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t (16; 21) (q24; q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of CBFA2T3. CBFA2T3 is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.

The ETO-2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of ETO-2 protein expression. This antibody has been meticulously developed and rigorously tested to ensure optimal performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The ETO-2 Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate and precise identification of ETO-2 protein in complex biological samples. Its superior affinity and selectivity make it an ideal choice for researchers and scientists working in the fields of molecular biology, cell biology, and cancer research.

This antibody is produced using state-of-the-art techniques, ensuring batch-to-batch consistency and reproducibility. It has been validated for use in multiple species, including human, mouse, and rat, allowing for versatile experimental designs and cross-species comparisons.

The ETO-2 Polyclonal Antibody is supplied as a liquid formulation, conveniently packaged in vials with appropriate storage conditions. It is recommended to store the antibody at -20°C to maintain its stability and activity. Each vial contains a sufficient amount of antibody for multiple experiments, minimizing the need for frequent reordering.

With its exceptional performance, reliability, and versatility, the ETO-2 Polyclonal Antibody is an indispensable tool for researchers seeking to unravel the intricate mechanisms underlying ETO-2 protein function and its involvement in various biological processes.