ERBeta Polyclonal Antibody

ESR2 encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.

The ERBeta Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of estrogen receptor beta (ERBeta) in various biological samples. This antibody is produced using a polyclonal approach, which ensures high affinity and specificity towards the target protein. The ERBeta Polyclonal Antibody is suitable for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The ERBeta Polyclonal Antibody is rigorously tested to ensure consistent and reliable performance. It has been validated for use in human, mouse, and rat samples, making it a versatile tool for researchers working in different fields. The antibody is supplied in a convenient format, with a concentration of 1 mg/mL, allowing for easy dilution and use in various assays.

The ERBeta Polyclonal Antibody is an essential tool for researchers studying the role of ERBeta in various physiological and pathological processes. Its high specificity and sensitivity make it an ideal choice for detecting ERBeta expression levels in different tissues and cell types. With its reliable performance and ease of use, the ERBeta Polyclonal Antibody is a valuable addition to any research laboratory.