ER Alpha Polyclonal Antibody

ESR1 encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein (estrogen receptor 1) localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

The ER Alpha Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of estrogen receptor alpha (ERα) protein expression in various biological samples. This antibody is produced using a polyclonal approach, ensuring a diverse range of epitope recognition and enhanced sensitivity. With its exceptional affinity and specificity, this antibody enables accurate and reliable identification of ERα in both research and clinical settings.

The ER Alpha Polyclonal Antibody exhibits excellent performance in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for its ability to detect ERα in a wide range of species, including human, mouse, and rat. This versatility makes it an ideal choice for researchers working with different model organisms.

This antibody is manufactured using high-quality materials and rigorous quality control measures to ensure consistent and reliable results. It is supplied as a liquid formulation, ready for immediate use without the need for any additional reagents or preparations. The ER Alpha Polyclonal Antibody is provided in a convenient size, allowing for multiple experiments and minimizing wastage.

In summary, the ER Alpha Polyclonal Antibody is a valuable tool for the study of estrogen receptor alpha protein expression. Its exceptional sensitivity, specificity, and versatility make it an essential component of any research or diagnostic laboratory. Trust in the reliability and performance of this antibody to enhance your understanding of ERα biology and contribute to advancements in the field of hormone signaling.