EphB1/2/3/4 Polyclonal Antibody

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The EPH receptor B1 encoded by EPHB1 is a receptor for ephrin-B family members.

The EphB1/2/3/4 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of EphB1, EphB2, EphB3, and EphB4 proteins. This antibody has been extensively validated for its exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The EphB family of receptor tyrosine kinases plays a crucial role in numerous cellular processes, such as cell adhesion, migration, and axon guidance. Dysregulation of EphB signaling has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Therefore, the accurate detection and quantification of EphB1, EphB2, EphB3, and EphB4 proteins are of utmost importance in understanding their functional roles and developing targeted therapies.

This polyclonal antibody has been meticulously developed using high-quality immunogens and advanced purification techniques to ensure superior specificity and sensitivity. It exhibits minimal cross-reactivity with other EphB family members, ensuring precise and reliable results. Additionally, this antibody has been extensively validated using a wide range of cell lines and tissues, guaranteeing its consistent performance across different experimental conditions.

The EphB1/2/3/4 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. Its optimized formulation ensures optimal performance and long-term stability, allowing for multiple experiments without compromising the results.

In summary, the EphB1/2/3/4 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of EphB1, EphB2, EphB3, and EphB4 proteins. Its exceptional performance in various applications, combined with its superior specificity and sensitivity, makes it an invaluable asset for researchers studying EphB signaling pathways and their implications in various diseases.