EphB1/2/3 Polyclonal Antibody

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The EPH receptor B1 encoded by EPHB1 is a receptor for ephrin-B family members.

The EphB1/2/3 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of EphB1, EphB2, and EphB3 proteins. This antibody has been extensively validated for its exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The EphB family of receptor tyrosine kinases plays a crucial role in numerous cellular processes, such as cell adhesion, migration, and axon guidance. The EphB1, EphB2, and EphB3 proteins are key members of this family and are known to be involved in various physiological and pathological conditions.

This polyclonal antibody has been meticulously developed using high-quality immunogens and advanced immunization techniques. It exhibits a high affinity and specificity towards EphB1, EphB2, and EphB3 proteins, ensuring accurate and reliable results in experimental studies.

The EphB1/2/3 Polyclonal Antibody demonstrates excellent sensitivity, enabling the detection of even low levels of target proteins. Its robust performance allows for the detection of endogenous EphB1, EphB2, and EphB3 proteins in various cell and tissue types.

Furthermore, this antibody has been rigorously tested to ensure minimal cross-reactivity with other related proteins, ensuring specificity in experimental applications. Its versatility allows for successful use in a wide range of species, including human, mouse, and rat.

In summary, the EphB1/2/3 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of EphB1, EphB2, and EphB3 proteins. Its exceptional performance, sensitivity, and specificity make it an ideal choice for researchers studying the functions and mechanisms of these important proteins in various biological processes.